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How Benchling secured multi-tenant AI agents with Amazon Bedrock AgentCore

Not a pilot. Benchling deployed AI agents running untrusted code across thousands of life-sciences tenants—here's how they locked it down.

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AI agents and the coordination of work.AI illustration by KeyNews
The KeyNews take

Why it matters

Multi-tenant agent security is becoming a solved problem. Benchling's defense-in-depth architecture (sandboxing + DNS firewall + VPC policies) shows how to run autonomous code generation safely at scale—a blueprint for enterprises deploying agents across customer data.

The key facts

11 to know
  1. Benchling deployed AI agents across thousands of life-sciences tenants

  2. Used Amazon Bedrock AgentCore Code Interpreter in VPC mode for sandboxing

  3. Combined Route 53 Resolver DNS Firewall with VPC endpoint policies to block data exfiltration

  4. Architecture addresses untrusted, agent-generated code execution

  5. Defense-in-depth approach: sandboxing + DNS controls + network policies

  6. Benchling deployed AI agents across thousands of tenants

  7. Used Amazon Bedrock AgentCore Code Interpreter in VPC mode

  8. Implemented defense-in-depth: Route 53 DNS Firewall + VPC endpoint policies

  9. Focused on blocking data exfiltration, including DNS-based attacks

  10. Life sciences / scientific code execution as use case

  11. Multi-tenant isolation and untrusted code execution as core problem

Go to the source

AWS Machine Learning Blogaws.amazon.com

Publisher excerpt: Learn how Benchling built a defense-in-depth security architecture to run untrusted, AI agent-generated scientific code across thousands of life sciences tenants using Amazon Bedrock AgentCore Code Interpreter in VPC mode, combined with Amazon Route 53 Resolver DNS Firewall and VPC endpoint…
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